Cell cultures are widely used in the biotechnology industry to produce valuable products. The process environment must be carefully monitored and controlled to maximize important factors such as product yield and quality. Real-time process measurements will lead to the automated process control necessary to ensure accurate substrate levels are maintained and that effective additions of important nutrients are made. In addition to enabling of process control, real-time monitoring also enables early detection of cultivation contamination and/or other failures. OptiEnz Sensors enables rapid and continuous monitoring of organic chemicals. The platform includes PC-based software, an instrument with an attached sensor probe, and replaceable sensor caps with multiple sensor tips. The sensor tips are unique to each chemical to be measured.